Nutritional support in the perioperative period of treatment of cancer patients: Retrospective cohort study

• DOI: 10.26442/18151434.2022.1.201479
• Publication Date: 2022-04-30T12:21:31Z
• Authors: Elena V. Gameeva; Alexandra M. Step...; Victoria E. Khoro...; Oleg V. Gridnev; Sergey V. Sviridov; Aleksandr E. Shes...
• Keywords: Enteral administration; Medical nutrition therapy; Gastrointestinal cancer

Background. The most important component of multimodality treatment cancer is nutritional support. management the correct full support in perioperative period will help to maintain body weight and muscle function, reduce frequency development postoperative complication severity hospital length stay. To provide necessary cover all energy requirements patients (30 kcal/kg per day), protein (1.5 g protein/kg day) eicosapentaenoic acid (2 g/day), applying clinical nutrition through appropriate routes administration (oral, enteral, parenteral or combined).
 Materials methods. trial studied dynamics status 400 oncological who underwent surgical at Hertsen Moscow Oncology Research Institute branch National Medical Radiology Centre from 2019 2021. were divided into 2 groups: main (n=200) control (n=200). group received consisted patients, according retrospective analysis with traditional approach study included deficiency confirmed by criteria, as well malignant neoplasms upper gastrointestinal tract (esophagus stomach), colon rectum, head neck.
 Results. application therapy can improve neck (the statistically significant increase 1 kgs 0.5 kgs, respectively). In colorectal cancer, during was stable tendency 0.4 kg. Perioperative for showed level both complete 2.8 4.1 g/l, respectively, serum albumin 5.2 3.3 respectively. absolute lymphocyte count increased trend level. No difference obtained cancer. Nutritional allowed total number complications 36%, including incidence anastomotic failure 3 times (p=0.014), infectious 1.5 (p=0.074), duration stay intensive care unit, inpatient 0.3 1.08 bed days, respectively (p0.05).
 Conclusion. reach more favorable course also lead a decrease early rehabilitation on other hand, unit hospital, reducing cost treating patients.