Safety and efficacy of a feed additive consisting of 6‐phytase produced by Aspergillus oryzae DSM 33737 (HiPhorius™) for all poultry, all Suidae and all fin fish (DSM Nutritional Products Ltd)

• DOI: 10.2903/j.efsa.2024.8663
• Publication Date: 2024-03-11T10:02:22Z
• Authors: Vasileios Bampidis; Giovanna Azimonti; Maria de Lourdes ...; Henrik Christensen; Birgit Dusemund; Mojca Durjava; Maryline Kouba; Marta López‐Alonso; Secundino López P...; Francesca Marcon; Baltasar Mayo; Alena Pechová; Mariana Petkova; Fernando Ramos; Roberto Edoardo V...; Ruud Woutersen; Noël Dierick; Henriqueta Louro; Giovanna Martelli; Luca Tosti; Montserrat Anguita; Joana P. Firmino; Matteo L. Innocenti; Elisa Petenatti; Fabiola Pizzo; Jordi Ortuño
• Keywords: Feed additive; Phytase; Animal Feed

Abstract Following a request from the European Commission, EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver scientific opinion safety efficacy of 6-phytase produced by genetically modified strain Aspergillus oryzae DSM 33737 (HiPhorius™ 10, 40, 20L 50L) as zootechnical feed additive for all poultry, Suidae fin fish. The FEEDAP concluded that genetic modification production does not give rise concerns. Based no observed adverse effect level identified subchronic oral toxicity study rats, considered safe fish at proposed conditions use. also use product is concern consumers environment. liquid formulations are skin eye irritants. two solid ones irritants but Owing lack data, cannot conclude sensitisation final additive. Due proteinaceous nature active substance (6-phytase), respiratory sensitiser. concludes efficacious when included diet poultry fattening reared laying/breeding, reproductive Suidae, sufficient could laying growing Suidae.