Vaccination of poultry against highly pathogenic avian influenza – Part 2. Surveillance and mitigation measures

• DOI: 10.2903/j.efsa.2024.8755
• Publication Date: 2024-04-18T09:09:25Z
• Authors: Søren Saxmose Nie...; Julio Alvarez; Dominique Joseph ...; Paolo Calistri; Elisabetta Canali; Julian Ashley Drewe; Bruno Garin‐Bastuji; Christian Gortázar; Mette S. Herskin; Virginie Michel; Miguel Ángel Mira...; Barbara Padalino; Helen Clare Roberts; Hans Spoolder; Karl Stahl; Antonio Velarde; Arvo Viltrop; Christoph Winckler; Alessio Bortolami; Claire Guinat; Timm Harder; Arjan Stegeman; Calogero Terregino; Barbara Lanfranchi; Ludovica Preite; Inma Aznar; Alessandro Broglia; Francesca Baldinelli; Jose Luis Gonzale...
• Keywords: Highly pathogenic

Abstract Selecting appropriate diagnostic methods that take account of the type vaccine used is important when implementing a vaccination programme against highly pathogenic avian influenza (HPAI). If effective, decreased viral load expected in samples for diagnosis, making molecular with high sensitivity best choice. Although serological can be reasonably sensitive, they may produce results are difficult to interpret. In addition routine monitoring, it recommended conduct isolation, genetic sequencing and phenotypic characterisation any HPAI virus detected vaccinated flocks detect escape mutants early. Following emergency vaccination, various surveillance options based on virological testing dead birds ('bucket sampling') at defined intervals were assessed effective early detection HPAIV prove disease freedom populations. For ducks, or live was as an strategy. This could also applied peri-vaccination zone establishments, while maintaining passive unvaccinated chicken layers turkeys, weekly bucket sampling ducks. To demonstrate > 99% confidence sufficiently following preventive monthly all up 15 per flock, coupled both flocks, recommended. Reducing increases 100%. enable safe movement poultry during laboratory examinations 72 h prior considered risk mitigation measure, clinical inspection; from existing activities carried out these used. this Opinion, several schemes vaccination.