Maternal microbiome and the impact in pre- and post-natal life

• DOI: 10.30574/gscbps.2024.29.2.0446
• Publication Date: 2024-12-02T23:55:17Z
• Authors: Óscar Adame-Barrón; Viviana López de...; Mayrin Molina-Amaya; Danna Nuñez-Valdez; Marlene Rivas-Ro...; Sabina Zúñiga-Am...; Brissia Lazalde
• Keywords: FOS: Biological sciences; Genetics; Alterations; Vaginal Seeding; Microbiome; Fetus Development

The maternal organism, including the microbiome of oral cavity, vaginal and intestinal microbiome, influences risk pregnancy outcomes related to fetal health even after birth. Recent research reveals that it is not only blood circulation, placenta or amniotic fluid contain bacteria. While interaction bacteria their metabolites with fetus newborn has serious consequences by causing diseases malformations. An alternative for women undergoing cesarean section seeding, a practice involves transferring fluids into body newborn. purpose provide beneficial babies. Moreover, factors such as probiotics, hygiene nutrition have been shown influence microbiome. consumption antibiotics during gestational stage could lead preterm delivery due deficiency gut Some hypotheses suggest alterations in neurodevelopment, example, thalamocortical axonogenesis, where its decreased limb sensitivity. Research on bacterial 16S rRNA sequence comparison makes possible establish phylogenetic relationships between prokaryotic organisms; this new identification method uses polyribonucleotide, distinguish individual bacteria, especially case difficult ones. It consists 3 steps: gene amplification from sample, nucleotide determination, analysis. As result, discovered does grow sterile environment.