Monocyte/High-Density Lipoprotein Ratio: An Indicator of Oxidative Stress and Disease Severity in Lichen Planus Patients

• DOI: 10.30733/std.2023.01684
• Publication Date: 2024-03-27T06:41:01Z
• Authors: Selami Aykut Temiz
• Keywords: Monocyte; High-density lipoprotein

Aim: Although the etiopathogenesis of lichen planus is not clearly known, it has been noticed to be associated with various factors such as drugs, infections, autoimmune factors, genetic and oxidative stress mechanisms. Oxidative implicated in pathogenesis diseases cancer chronic inflammatory diseases. Complete blood count parameters can utilized diagnostic biomarkers for many related processes. In recent clinical studies, shown that monocyte/high-density lipoprotein (HDL) ratio (MHR) may useful a marker dermatoses. However, far we know, relationship between monocyte/HDL cases studied literature yet. Materials Methods: The files who were followed up dermatology clinic tertiary university hospital February 2018 July 2021 reviewed retrospectively. There 201 participants analysis, including 99 histopathologically clinically verified LP 102 age sex-matched controls. Results: Monocyte values (p=0.16) HDL levels (p=0.26) statistically different both groups, but MHR value (p=0.04) was detected significantly higher group than control group. oral cases, whilst disease severity score uric acid correlated (p=0.11), CRP (p=0.03) (p=0.001) values. Conclusions: study, found patients compared Again, had better correlation mucosa CRP. We suggest potential index assess activity follow-up planus. Keywords: Lichen planus, mucosa,