Prevalence of Generalized Retinal Dystrophy in Denmark

• DOI: 10.3109/09286586.2014.929710
• Publication Date: 2014-06-25T10:29:27Z
• Authors: Mette Bertelsen; Hanne Jensen; Jesper F. Bregnhøj; Thomas Rosenberg
• Keywords: Danish; Dystrophy

Purpose: Generalized retinal dystrophy is a frequent cause of visual impairment and blindness in younger individuals subject new clinical intervention trials. Nonetheless, there are few nation-wide population-based epidemiological data generalized dystrophy. The purpose this study was to examine the prevalence diagnostic spectrum Danish population.Methods: A cross-sectional with from Retinitis Pigmentosa Registry that comprises all patients Denmark chorioretinal dystrophies 19th century present. Among 3076 registered cases, primary diagnosis assessed by chart review, including fundus photographs electroretinograms. Demographic on population were retrieved Statistics Denmark.Results: Of 5,602,628 citizens January 1, 2013, 1622 as having alive living Denmark, corresponding 1:3,454. In 28% cases eye condition part syndrome, while remaining 72% had disease only. Aside simplex (45%), most common hereditary pattern autosomal recessive (23%).Conclusion: This survey demonstrates 1:3454. Many subjects trials, can help assess burden future need for treatment.