Unusual Presentation of a Rare Cancer: Histiocytic Sarcoma in the Brain 16 Years After Treatment for Acute Lymphoblastic Leukemia

• DOI: 10.3121/cmr.2012.1092
• Publication Date: 2013-02-14T22:40:27Z
• Authors: S. Chalasani; M. R. Hennick; W. G. Hocking; G. R. Shaw; B. Lawler
• Keywords: Histiocytic sarcoma; Presentation (obstetrics)

Histiocytic sarcoma (HS) is a very rare hematopoietic neoplasm that has been reported in association with other hematological malignancies. Presentation of HS the central nervous system even less common. Diagnosis requires presence histiocytic markers and systematic exclusion cell lineages. Primary tumors are aggressive generally have poor outcomes. There no standard treatment guidelines due to lack clinical trials limited number case reports. Here we present unique two primary lesions brain, refractory systemic radiation therapies, developed after being treated for T-cell acute lymphoblastic leukemia 16 years prior.