Synthesis and Characterization of Copper Oxide Nanoparticles Isolated from Acmella oleracea and Study of Antimicrobial and Phytochemical Properties

• DOI: 10.3126/arj.v5i1.73521
• Publication Date: 2025-01-08T10:35:16Z
• Authors: Sujan Dhungana; Anusa Gauli; Laxmi Tiwari; Devendra Khadka; Surendra Kumar Ga...; Megh Raj Pokhrel; Janaki Baral; Bhoj Raj Poudel
• Keywords: Phytochemical

This study utilized a green synthesis approach to produce CuO nanoparticles employing flower extract of Acmella oleracea where plant-derived biomolecules served as natural reducing and stabilizing agents. The synthesized were characterized through X-ray diffraction (XRD), UV-Vis spectroscopy, Fourier Transform Infrared (FTIR) analysis. XRD suggested the monoclinic phase that belong C2/c space group with crystallite size 17.35 nm on average. band gap was calculated using Tauc model which 2.27 eV. Phytochemical screening confirmed presence alkaloids, essential for nanoparticle formation, Mayer’s, Dragendorff’s, Wagner’s, Hager’s tests. Antimicrobial tests showed had significant activity against microbes such Escherichia coli, Staphylococcus aureus, Candida albicans, inhibition zones 1.5 1.8 cm. These findings highlight potential mediated biomedical environmental applications.