Occurrence of urinary tract infection among children attending Gandaki Medical College Teaching Hospital and Research Center, Pokhara, Nepal

• DOI: 10.3126/ijim.v2i3.8665
• Publication Date: 2013-10-11T11:08:53Z
• Authors: G Gautam; S Regmi; NT Magar; B Subedi; T Sharma; SM Regmi
• Keywords: Amikacin; Citrobacter

INTRODUCTION: Urinary tract infection (UTI) is considered as the most common bacterial infectious disease seen among pediatric patients. Most commonly, members of Enterobacteriaceae, particularly uropathogenic strains E. coli and Enterobacter spp. are primary causative pathogens UTI in different part world. Emergence antimicrobial resistance rates recovered from urinary infections an increasing problem specific region. MATERIALS AND METHODS: Prevalence anti microbial susceptibility pattern uropathogens isolated children attending Gandaki Medical College Teaching Hospital Reserch Center (GMC) Nepal. A total 155 aged upto 15 years were included this study. Urine cultures carried out isolates identified by Gram staining conventional biochemical methods. Antimicrobial testing was performed disk diffusion method according to Clinical Laboratory Standards Institute (CLSI). RESULTS: In present study 21.3 % sample size, showed significant growth. frequently occurring pathogen (39.40%), followed Proteus 21.2%, Citrobacter Streptococcus faecalis (12.1%) Klebsiella (9.1%), Staphylococcus aureus (3.0%). Susceptibility rate 69.2% Gentamycin Amikacin, 53.8% Norfloxacin, 38.4% Nalidixic acid Norfloxacin. CONCLUSIONS: Pediatric urine culture becoming increasingly resistant commonly used antibiotics. Finally, we suggest that empirical antibiotic selection should be based on knowledge local prevalence organisms sensitivities rather than universal guidelines. DOI: http://dx.doi.org/10.3126/ijim.v2i3.8665 Int J Infect Microbiol 2013;2(3):82-86