Status of liver stiffness following directly acting antiviral treatment in patients with chronic hepatitis C: A Nepalese study

• DOI: 10.3126/jcmsn.v13i3.17852
• Publication Date: 2017-10-19T03:51:10Z
• Authors: Dilip Sharma; Sudhamshu KC; Ananta Shrestha; Bikash Jaishi
• Keywords: Transient elastography; Sofosbuvir; Liver disease; Hepatitis C; Chronic liver disease

Background & Objectives:Chronic hepatitis C is one of the leading causes chronic liver disease in our country. With introduction directly acting antivirals, many patients are benefitted these days. Transient elastography newer technologies for measuring stiffness and quantifying fibrosis has excellent accuracy diagnosis with C. Our study analyzes changes its associated factors treated antivirals (DAAs).Materials Methods: One hundred seven C, who were DAAs (Sofosbuvir 400 mg velpatasvir 100mg) have significant (>7.0 kPa) at baseline included. Liver was measured time enrollment, after completion fibroscan analyzed. Results:The showed decrease end treatment, which continued treatment only achieved a sustained virological response.Conclusion: decreased following 12 weeks successful therapy response.