Study on the Bioactive Constituents and <i>in vitro</i> Antioxidant and <i>in vivo</i> Anti-inflammatory Activities of Extracts from the Fruits of <i>Ziziphus Jujuba</i> Mill. cv. <i>Jinsixiaozao</i> Hort

• DOI: 10.3136/fstr.23.417
• Publication Date: 2017-07-27T18:14:48Z
• Authors: Xuejiao Li; Xia Li; Bin Zhou; Shuli Man; Wenyuan Gao; Songsong Jing
• Keywords: Petroleum ether; Anti-inflammatory; Stigmasterol; Terpene; Carrageenan

The aims of this study were to investigate the antioxidant and anti-inflammatory effects extracts from fruits Ziziphus jujuba Mill. cv. jinsixiaozao Hort (ZJMH) its active chemical constituents. For activity, reducing power, DPPH β-carotene bleaching inhibition assay used. Ethyl acetate extract exhibited strongest potential in all models. petroleum ether showed (32.86%) against carrageenan-induced paw edema, which also displayed potent activity xylene-induced ear edema (41.52%). contents phenolic acids, flavonoids, triterpenes, anthocyanins, triterpenoid saponins different observed. Moreover, seven compounds first isolated considerable especially alphitolic acid stigmasterol. results that ZJMH can be a natural agent.