Influence of Oryzanol and Ferulic Acid on the Lipid Metabolism and Antioxidative Status in High Fat-Fed Mice

• DOI: 10.3164/jcbn.09-98
• Publication Date: 2010-03-01T06:05:18Z
• Authors: Myoung Jin Son; Catherine W. Rico; Seok Hyun Nam; Mi Young Kang
• Keywords: Hyperlipidemia; High-density lipoprotein

The comparative effects of oryzanol and ferulic acid on the lipid metabolism antioxidative status high fat-fed mice were investigated. given a diet containing 17% fat (HF), supplemented with (HF-O) or for 7 weeks. control (NC) fed normal diet. HF exhibited increased body weight gain, plasma hepatic total cholesterol triglyceride concentrations, peroxidation rate, reduced high-density lipoprotein level. In general, they also showed lower antioxidant higher lipid-regulating enzymes activities relative to that NC group. Addition in counteracted these fat-induced hyperlipidemia oxidative stress via faecal excretion regulation lipogenic activities. This study illustrates have relatively similar hypolipidemic actions could be effective lowering risk diet-induced obesity.