Hyperglycemia, excess weight, and history of hypertension as risk factors for poor outcome and cerebral infarction after aneurysmal subarachnoid hemorrhage

• DOI: 10.3171/jns.2005.102.6.0998
• Publication Date: 2009-05-13T18:04:03Z
• Authors: Seppo Juvela; Jari Siironen; Johanna Kuhmonen
• Keywords: Adult; Blood Glucose; Male; Cerebral Infarction; Middle Aged; Subarachnoid Hemorrhage; Severity of Illness Index; 3. Good health; 03 medical and health sciences; Postoperative Complications; Treatment Outcome; 0302 clinical medicine; Predictive Value of Tests; Risk Factors; Hyperglycemia; Hypertension; Humans; Female; Obesity; Prospective Studies; Aged

Object. Stress-induced hyperglycemia has been shown to be associated with poor outcome after aneurysmal subarachnoid hemorrhage (SAH). The authors prospectively tested whether hyperglycemia, independent of other factors, affects patient outcomes and the occurrence cerebral infarction SAH. Methods. Previous diseases, health habits, medications, clinical condition, neuroimaging variables were recorded for 175 patients SAH who admitted hospital within 48 hours bleeding. plasma level glucose was measured at admission fasting value in morning aneurysm occlusion. Factors found independently predictive 3 months onset appearance by performing multiple logistic regression. Plasma values age, body mass index (BMI), history hypertension, amount or intraventricular blood, shunt-dependent hydrocephalus, variables, infarction. When considered subarachnoid, intraventricular, intracerebral predicted (per millimole/liter odds ratio [OR] 1.24 a 95% confidence interval [CI] 1.02–1.51). After an adjustment made duration temporary artery occlusion during surgery, BMI significant predictor kilogram/square meter OR 1.15 CI 1.02–1.29) finding on follow-up computerized tomography scan. Hypertension (OR 3.11, 1.11–8.73)—but not 1.06, 0.87–1.29)—also when instead BMI. Conclusions. Independent severity bleeding, seems impair outcome, excess weight hypertension appear elevate risk