Angle-Corrected Imaging Transcranial Doppler Sonography versus Imaging and Nonimaging Transcranial Doppler Sonography in Children with Sickle Cell Disease

• DOI: 10.3174/ajnr.a0591
• Publication Date: 2008-08-19T18:40:15Z
• Authors: J. Krejza; W. Rudzinski; M.A. Pawlak; M. Tomaszewski; R. Ichord; J. Kwiatkowski; D. Gor; E.R. Melhem
• Keywords: Doppler sonography; Transcranial Doppler; Color doppler

<b>BACKGROUND AND PURPOSE:</b> Nonimaging transcranial Doppler sonography (TCD) and imaging TCD (TCDI) are used for determination of the risk stroke in children with sickle cell disease (SCD). The purpose was to compare angle-corrected, uncorrected TCDI, blood flow velocities SCD. <b>MATERIALS METHODS:</b> A total 37 (mean age, 7.8 ± 3.0 years) without intracranial arterial narrowing determined MR angiography, were studied use TCDI at same session. Depth insonation mean correction angle terminal internal carotid artery (ICA) middle (MCA), anterior (ACA), posterior (PCA) cerebral arteries compared a paired <i>t</i> test. <b>RESULTS:</b> Two not found on 15 TCD. Average MCA, ACA, ICA, PCA 31°, 44°, 25°, 29°, respectively. depth all did differ significantly; however, individual differences varied substantially. significantly lower than velocities, respectively, right left sides SD): 106 22 cm/s 111 33 versus 130 19 134 26 cm/s; 90 14 98 27 117 18 119 23 74 24 88 25 105 31 PCA, 84 82 21 95 94 20 cm/s. angle-corrected statistically different except higher values ACA PCA. <b>CONCLUSION:</b> but from velocities. identifies major more effectively