Distinguishing between Germinomas and Pineal Cell Tumors on MR Imaging

• DOI: 10.3174/ajnr.a2806
• Publication Date: 2011-12-16T01:31:49Z
• Authors: N. Dumrongpisutikul; J. Intrapiromkul; D.M. Yousem
• Keywords: Germinoma; Pinealoma; Coefficient of variation

Tumors of pineal cell origin have different prognosis and treatment than those germ origin. The recent literature suggests that these tumors often look alike. Our study aimed to differentiate between tumor germinoma based on ADC values, the homogeneity mass, MR imaging characteristics.We enrolled 20 patients who had pretreatment scans with histologic verification germinomas. were measured for values by coefficient variation T1WI T2WI signal intensity values.The subjects (8 females 12 males) ranged in age from 1.5-64.9 years, a mean 23.9 years (SD 17.7 years). germinomas was 13.7 3.8 years), less 29.4 19.9 years; P = .016). These 2 groups showed no significant difference coefficients T1WI, T2WI, images. However, statistically higher (mean 1590.69 ± 532.96 × 10(-6) mm(2)/s) 883.58 317.48 mm(2)/s; .02). An accuracy 89.5%, sensitivity 83.3%, specificity 92.3%, PPV NPV 92.3% yielded an threshold 1250.00 mm(2)/s.Germinomas (P .02), younger. Otherwise, there definitive characteristics distinguished