Assessment of Intracranial Collaterals on CT Angiography in Anterior Circulation Acute Ischemic Stroke

• DOI: 10.3174/ajnr.a4117
• Publication Date: 2014-10-17T10:07:53Z
• Authors: L.L.L. Yeo; P. Paliwal; H.L. Teoh; R.C. Seet; B.P. Chan; E. Ting; N. Venketasubrama...; W.K. Leow; B. Wakerley; Y. Kusama; R. Rathakrishnan; V.K. Sharma
• Keywords: Stroke; Collateral circulation; Acute stroke

<h3>BACKGROUND AND PURPOSE:</h3> Intracranial collaterals influence the prognosis of patients treated with intravenous tissue plasminogen activator in acute anterior circulation ischemic stroke. We compared methods scoring on pre-tPA brain CT angiography for predicting functional outcomes <h3>MATERIALS METHODS:</h3> Two hundred consecutive stroke IV-tPA during 2010–2012 were included. independent neuroradiologists evaluated intracranial by using Miteff system, Maas modified Tan scale, and Alberta Stroke Program Early Score 20-point methodology. Good extremely poor at 3 months defined Rankin Scale scores 0–1 5–6 points, respectively. <h3>RESULTS:</h3> Factors associated good outcome univariable analysis younger age, female sex, hypertension, diabetes mellitus, atrial fibrillation, small infarct core (ASPECTS ≥8), vessel recanalization, lower NIHSS scores, according to methodology, ASPECTS On multivariable logistic regression, only (OR, 1.186 per point; 95% CI, 1.079–1.302; <i>P</i> = .001), recanalization 5.599; 1.560–20.010; .008), method 3.341; 1.203–5.099; .014) predictors outcome. Poor system 2.592; 1.113–6.038; .027), 2.580; 1.075–6.187; .034), ≤5 points 2.685; 1.156–6.237; .022) outcomes. <h3>CONCLUSIONS:</h3> Only is reliable favorable thrombolyzed However, can be predicted most existing collaterals.