Combination of Imaging Features and Clinical Biomarkers Predicts Positive Pathology and Microbiology Findings Suggestive of Spondylodiscitis in Patients Undergoing Image-Guided Percutaneous Biopsy

• DOI: 10.3174/ajnr.a6623
• Publication Date: 2020-06-18T19:12:08Z
• Authors: S. Kihira; C. Koo; K. Mahmoudi; T. Leong; X. Mei; B. Rigney; A. Aggarwal; A.H. Doshi
• Keywords: Spondylodiscitis; Surgical pathology; Discitis; Anatomical pathology

<h3>BACKGROUND AND PURPOSE:</h3> Pathology and microbiology results for suspected spondylodiscitis on MR imaging are often negative in up to 70% of cases. We aimed predict whether features will add diagnostic value when combined with clinical biomarkers positive findings pathology and/or from percutaneous biopsy. <h3>MATERIALS METHODS:</h3> In this retrospective single-center institutional review board–approved study, patients radiologically having undergone biopsies were assessed. Demographic characteristics, laboratory values, tissue blood cultures collected. used as end points. Three independent observers provided imaging–based scoring typical spondylodiscitis. Multivariate logistic regression receiver operating characteristic analysis performed determine an optimal combination predicting biopsy suggestive <h3>RESULTS:</h3> Our patient cohort consisted 72 patients, whom 33.3% (24/72) had The mean age was 63 ± 16 years a male/female ratio 41:31. Logistic revealed area under the curve 0.72 0.68 microbiology. Epidural enhancement improved predictive performance 0.87 0.78 <h3>CONCLUSIONS:</h3> demonstrate that epidural added help which undergoing have