Administration of Dried Aloe vera Gel Powder Reduced Body Fat Mass in Diet-Induced Obesity (DIO) Rats

• DOI: 10.3177/jnsv.58.195
• Publication Date: 2012-08-09T18:33:33Z
• Authors: Eriko MISAWA; Miyuki TANAKA; Kazumi NABESHIMA; Kouji NOMAGUCHI; Muneo YAMADA; Tomohiro TOIDA; Keiji IWATSUKI
• Keywords: Aloe Vera

The aim of the present study was to investigate anti-obesity effects Aloe vera gel administration in male Sprague-Dawley (SD) rats with diet-induced obesity (DIO). SD at 7 wk age were fed either a standard diet (10 kcal% fat) (StdD) or high-fat (60 (HFD) during experimental period. Four weeks after HFD-feeding, DIO (11 age) orally administered two doses powder (20 and 200 mg/kg/d) for 90 d. Body weights (g) body fat (%) HFD significantly higher than those StdD-fed rats. Although modest decrease weight observed dried powder, both subcutaneous visceral reduced gel-treated Serum lipid parameters elevated by also improved treatment. oxygen consumption (VO(2)), an index energy expenditure, decreased HFD-fed compared that Administration reversed change VO(2) These results suggest intake accumulation, part, stimulation expenditure. might be beneficial prevention improvement obesity.