Erythromycin Resistance in Streptococcus pyogenes in Italy

• DOI: 10.3201/eid0602.000212
• Publication Date: 2009-09-01T18:06:25Z
• Authors: Matteo Bassetti; Graziana Manno; Andrea Collidà; Alberto Ferrando; Giorgio Gatti; Elisabetta Ugolotti; Mario Cruciani; Dante Bassetti
• Keywords: Streptococcus Pyogenes; Telithromycin; Macrolide Antibiotics

In a prospective study of acute pharyngitis in Italian children, 69 (38.3%) 180 isolates Streptococcus pyogenes were resistant to macrolides. S. was eradicated 12 (63.1%) 19 patients with erythromycin-resistant treated clarithromycin and 22 (88%) 25 erythromycin-susceptible strains. The constitutive-resistant phenotype correlated failure macrolide treatment.