Pathologic Studies of Fatal Cases in Outbreak of Hand, Foot, and Mouth Disease, Taiwan

• DOI: 10.3201/eid0701.700146
• Publication Date: 2013-08-12T16:05:20Z
• Authors: Wun-Ju Shieh; Shih-Ming Jung; Chuen Hsueh; Tseng-Tong Kuo; Anthony Mounts; Umesh Parashar; Chen Fu Yang; Jeannette Guarner; Thomas G. Ksiazek; Jacqueline Dawson; Cynthia Goldsmith; Gwong-Jen J. Chang; Steve M. Oberste; Mark A. Pallansch; Larry J. Anderson; Sherif R. Zaki
• Keywords: Hand-foot-and-mouth disease; Foot (prosody); Enterovirus 71

In 1998, an outbreak of enterovirus 71-associated hand, foot, and mouth disease occurred in Taiwan. Pathologic studies two fatal cases with similar clinical features revealed different causative agents, emphasizing the need for postmortem examinations modern pathologic techniques investigation.