Increasing Incidence of Mucormycosis in University Hospital, Belgium

• DOI: 10.3201/eid1609.100276
• Publication Date: 2010-08-23T14:55:28Z
• Authors: Veroniek Saegeman; Johan Maertens; Wouter Meersseman; Isabel Spriet; Eric Verbeken; Katrien Lagrou
• Keywords: Adult; Male; Antifungal Agents; Adolescent; Infectious and parasitic diseases; RC109-216; Hospitals, University; Young Adult; 03 medical and health sciences; Belgium; Risk Factors; voriconazole; Humans; Mucormycosis; hematologic neoplasms; Child; Aged; 0303 health sciences; Incidence; Fungi; R; Dispatch; Middle Aged; Triazoles; invasive fungal disease; 3. Good health; Pyrimidines; Hematologic Neoplasms; hematopoietic stem cell transplantation; incidence; Medicine; Female; Voriconazole

To determine why incidence of mucormycosis infections was increasing in a large university hospital in Belgium, we examined case data from 2000-2009. We found the increase was not related to voriconazole use but most probably to an increase in high-risk patients, particularly those with underlying hematologic malignancies.