ALK-Negative Inflammatory Myofibroblastic Tumor: A Challenging Case in a Premature Newborn

• DOI: 10.3233/npm-230007
• Publication Date: 2023-05-30T15:30:51Z
• Authors: C. Regaieg; M. Triki; T. Cheikrouhou; A.B. Thabet; S. Charfi; M.B. Dhaou; T. Boudawara; A.B. Hamed; N. Hmida
• Keywords: Histopathology; Desmin; Histopathological examination

Inflammatory myofibroblastic tumors (IMT) are rare borderline with a variable histological appearance that may mimic multiple mesenchymal tumors. We present case of challenging abdominal mass discovered in premature newborn. The histopathology showed bland proliferation associated an inflammatory infiltrate was positive for smooth muscle actin and desmin but negative anaplastic lymphoma kinase (ALK) protein. diagnosis ALK-negative IMT established. tumor partially resected. After six months follow-up, the residual remained stable, patient asymptomatic. correct subsequent treatment require appropriate histopathological, immunohistochemical, sometimes genetic examination. Further research has to be conducted help clinicians make plan.