HUMAN ADAPTATION TO THE CONDITIONS OF THE FAR NORTH: EMPHASIS ON THE CORRECTION OF THE MICROBIAL-TISSUE COMPLEX OF THE GASTROINTESTINAL TRACT

• DOI: 10.33396/1728-0869-2021-2-4-12
• Publication Date: 2021-03-16T11:16:46Z
• Authors: S. P. Salikova; A. A. Vlasov; V. B. Grinevich
• Keywords: Flora; Intestinal Permeability; Enteric Nervous System

Severe natural and climatic conditions, special features of work, rest, nutrition, physical activity communication people in the Arctic zone can seriously affect intestinal microbiota. This review summarizes research results indicating decrease number, changes morphological biological properties lacto-and bifidobacteria, activation opportunistic pathogenic flora inhabitants Far North. Mechanisms a complex interplay between human body microbiocenosis are presentd The influence microbiota on permeability, nerve endings enteral nervous system, immuno-inflammatory processes is shown. Data participation microbial molecules modulation neurotransmission brain spinal cord, hypothalamo-pituitary-adrenal system summarized. positive effects pro-, prebiotics dietary supplements correction conditions associated with environmental occupational stress highlighted.