A Simplified Formula Using Early Blood Gas Analysis Can Predict Survival Outcomes and the Requirements for Extracorporeal Membrane Oxygenation in Congenital Diaphragmatic Hernia

• DOI: 10.3346/jkms.2013.28.6.924
• Publication Date: 2013-06-07T07:30:02Z
• Authors: Hye Won Park; Byong Sop Lee; Gina Lim; Yong-Sung Choi; Ellen Ai-Rhan Kim; Ki-Soo Kim
• Keywords: pCO2; Extracorporeal

The aims of this study were to investigate whether early arterial blood gas analysis (ABGA) could define the severity disease in infants with congenital diaphragmatic hernia (CDH). We conducted a retrospective over 21-yr period diagnosed CDH. Outcomes defined as death before discharge, and extracorporeal membrane oxygenation requirements (ECMO) or death. A total 114 included study. investigated simplified prediction formula [PO2-PCO2] values at 0, 4, 8, 12 hr after birth associated mortality, ECMO area under curve (AUC) receiver operating characteristic was used determine optimum ABGA for predicting outcomes. value best predictor mortality (AUC 0.803, P < 0.001) 4 most reliable 0.777, 0.001). from can reliably predict outcomes