Neural Changes Associated with Emotion Processing in Children Experiencing Peer Rejection: A Functional MRI Study

• DOI: 10.3346/jkms.2014.29.9.1293
• Publication Date: 2014-09-05T04:25:54Z
• Authors: Hyun-Seung Lee; Ji-Eun Lee; Kyoung-Uk Lee; Young-Hoon Kim
• Keywords: Male; Brain Mapping; Depression; Emotions; Brain; Anxiety; Magnetic Resonance Imaging; Peer Group; 3. Good health; Facial Expression; 03 medical and health sciences; 0302 clinical medicine; Psychological Distance; Surveys and Questionnaires; Humans; Original Article; Female; Child

This study was performed to investigate differences between children who did and not experience peer rejection in psychological state through surveys emotion processing during an interpersonal stress challenge task reflect naturalistic face-toface relationships.A total of 20 right-handed children, 10 12 yr age, completed selfrating questionnaires inquiring about school, depression, anxiety.They then underwent simulating conditions emotional stress, reaction positive, negative neutral facial expression stimuli, using feedbacks, functional magnetic resonance imaging (FMRI) for analysis neural correlates the task.Ten were peer-rejection group, whereas remainder control group.Based on behavioral results, group exhibited elevated levels anxiety, trait anxiety social as compared group.The FMRI results revealed that greater remarkably more extensive activation brain regions encompassing amygdala, orbitofrontal cortex ventrolateral prefrontal response feedback stimuli faces.The different reactivities characterizing relationships may be present do rejection.