Prevalence and Incidence of Neuromyelitis Optica Spectrum Disorder in Korea: Population Based Study

• DOI: 10.3346/jkms.2020.35.e115
• Publication Date: 2020-03-11T06:37:21Z
• Authors: Hye Lim Lee; Jae Young Kim; Jin Myoung Seok; Yoon-Ho Hong; Nam Gu Lim; Ha Young Shin; Byung-Jo Kim; Soon-Young Hwang; Ju-Hong Min; Byoung Joon Kim
• Keywords: Neuromyelitis Optica; Spectrum disorder

Background: Although neuromyelitis optica spectrum disorder (NMOSD) is known to be a rare disease, its prevalence and incidence have not yet been studied in Korea.We performed population-based study examine the of NMOSD Korea using data from Korean National Health Insurance (NHI) claims database.Methods: Data 2013 2017 were obtained, with washout period set as 2014.The 2016 calculated population census data.Subjects divided into 5 groups at 15-year intervals, depending on age which diagnostic code was entered.The relative risk (RR) for each group compared oldest (≥ 60 years) group.Results: The overall estimated 3.36 3.56 per 100,000 individuals, an 0.41 0.65 individuals-year 2017, respectively.The mean 43.08 (standard deviation, 14.56) years, ratio male females 1:4.7.The higher female individuals aged between 30 59 years (RR, 2.8-3.05;P < 0.05).Conclusion: Nationwide 3.56/100,000 0.65/100,000-year respectively.