Clinical Course and Outcomes of Patients with Severe Acute Respiratory Syndrome Coronavirus 2 Infection: a Preliminary Report of the First 28 Patients from the Korean Cohort Study on COVID-19

• DOI: 10.3346/jkms.2020.35.e142
• Publication Date: 2020-04-15T23:34:57Z
• Authors: Eu Suk Kim; Bum Sik Chin; Chang Kyung Kang; Nam Joong Kim; Yu Min Kang; Jae-Phil Choi; Dong Hyun Oh; Jeong-Han Kim; Boram Koh; Seong Eun Kim; Na Ra Yun; Jae-Hoon Lee; Jin Yong Kim; Yeonjae Kim; Ji Hwan Bang; Kyoung-Ho Song; Hong Bin Kim; Ki-hyun Chung; Myoung-don Oh
• Keywords: Sore throat; Coronavirus; Viral Pneumonia

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected pneumonia emerged in Wuhan, China December 2019.In this retrospective multicenter study, we investigated the clinical course and outcomes of novel disease 2019 (COVID-19) from early cases Republic Korea.Methods: All confirmed by real time polymerase chain reaction were enrolled 1st to 28th patient nationwide.Clinical data collected analyzed for changes severity including laboratory, radiological, virologic dynamics during progression illness.Results: The median age was 40 years (range, 20-73 years) 15 (53.6%) patients male.The most common symptoms cough (28.6%) sore throat (28.6%), followed fever (25.0%).Diarrhea not (10.7%).Two had no symptoms.Initial chest X-ray (CXR) showed infiltration 46.4% patients, but computed tomography scan 88.9% (16/18) patients.Six (21.4%) required