Intravenous Versus Perineural Dexamethasone for Reducing Rebound Pain After Interscalene Brachial Plexus Block: A Randomized Controlled Trial

• DOI: 10.3346/jkms.2023.38.e183
• Publication Date: 2023-05-12T07:02:52Z
• Authors: Hyun Jung Lee; Jae Hee Woo; Ji Seon Chae; Youn Jin Kim; Sang-Jin Shin
• Keywords: Ropivacaine; Brachial plexus block

Interscalene brachial plexus block (ISB) is a common regional technique to manage acute postoperative pain for arthroscopic rotator cuff tear repair. However, rebound may compromise its overall benefit. Our aim was investigate the primary hypothesis that perineural and intravenous dexamethasone have different effects on after resolution of ISB repair.Patients aged ≥ 20 years scheduled elective repair under general anesthesia with preoperative were included. The participants randomized receive either perineurally (perineural group) or intravenously (intravenous group). In group, patients received 12 mL 0.5% ropivacaine containing 5 mg dexamethasone; simultaneously, 1 0.9% normal saline administered intravenously. ropivacaine; outcome difference in score (0-10 numeric rating scale) between before resolution. secondary outcomes incidence pain; onset, duration, intensity time first analgesic request; pain-related sleep disturbance.A total 71 group (n = 36) 35). After resolution, scores increased significantly more (mean ± standard deviation, 4.9 2.1) compared (4.0 1.7, P 0.043). duration prolonged (median [interquartile range], 19.9 [17.2-23.1] hours) than (15.1 [13.7-15.9] hours, < 0.001). disturbance during week higher (rebound pain: 44.4% vs. 20.0%, 0.028; disturbance: 55.6% 25.7%, 0.011). similar two groups.Although provided longer analgesia, beneficial reducing increase pain, disturbance.Clinical Research Information Service Identifier: KCT0006795.