Comparison of intravenous lignocaine and intravenous dexmedetomidine in attenuating pressor response to laryngoscopy and endotracheal intubation in controlled hypertensive patients

• DOI: 10.33545/26643766.2021.v4.i2b.244
• Publication Date: 2021-06-07T04:10:15Z
• Authors: Dr. Noopur Singh; Dr. Khandat Dhana...
• Keywords: Dexmedetomidine

Background: Laryngoscopy and endotracheal intubation form the basis of controlling patient's airway during general anaesthesia or artificial ventilation which may have deleterious respiratory, neurological, cardiovascular effects associated with hemodynamic changes. These transient responses are usually well tolerated by normotensive patients cause no consequences in them. Patients hypertension known to exhibit exaggerated pressor response complications like cardiac failure, myocardial infarction cerebral haemorrhage. So, our aim was evaluate effect intravenous preservative free 2 % Lignocaine (1.5 mg/kg) attenuating laryngoscopy tracheal compared Dexmedetomidine (1 mcg/kg).Methodology: In this study, 60 patients, aged between 40-60 years either sex k/c/o Hypertension taking some antihypertensive medications belonging ASA class II included randomly allocated groups each 30. Group L, had received 1.5 mg/kg IV 3 minutes before intubation. D, 1mcg/kg diluted 50 ml NS as an infusion over 10 induction. Result: The study revealed that there is significant difference (p value < 0.05) two respect heart rate, systolic, diastolic mean arterial BP. Conclusion: significantly attenuates haemodynamic stability controlled hypertensive patients.