Multilineage-differentiating stress-enduring cells: a powerful tool for tissue damage repair

• DOI: 10.3389/fcell.2024.1380785
• Publication Date: 2024-05-30T04:37:07Z
• Authors: Hanyun Que; Erziya Mai; Yanting Hu; Hong Li; Wenxin Zheng; Yuchen Jiang; Feiruo Han; Xuedong Li; Puyang Gong; Jian Gu
• Keywords: Regenerative Medicine; Homing (biology); Tissue Repair; Cell type

Multilineage-differentiating stress-enduring (Muse) cells are a type of pluripotent cell with unique characteristics such as non-tumorigenic and differentiation ability. After homing, Muse spontaneously differentiate into tissue component supplement damaged/lost to participate in repair. Importantly, can survive injured for an extended period, stabilizing promoting In addition, it has been confirmed that injection exogenous exerts anti-inflammatory, anti-apoptosis, anti-fibrosis, immunomodulatory, paracrine protective effects vivo . The discovery is important breakthrough the field regenerative medicine. article provides comprehensive review characteristics, sources, potential mechanisms repair regeneration. This serves foundation further utilization key clinical tool