Human and animal exposure to newly discovered sand fly viruses, China

• DOI: 10.3389/fcimb.2023.1291937
• Publication Date: 2024-01-03T04:31:55Z
• Authors: Xiaohui Yao; Qikai Yin; Xiaodong Tian; Yuke Zheng; Hongyan Li; Shihong Fu; Zhengmin Lian; Yijia Zhang; Fan Li; Weijia Zhang; Ying He; Ruichen Wang; Bin Wu; Kai Nie; Songtao Xu; Jingxia Cheng; Xiangdong Li; Huanyu Wang; Guodong Liang
• Keywords: Sandfly; Isolation; Phlebotomus

Introduction The Hedi virus (HEDV) and Wuxiang (WUXV) are newly discovered Bunyaviruses transmitted by sandflies. geographical distribution of isolation these two viruses continues to expand it has been reported that WUXV causes neurological symptoms even death in suckling mice. However, little is known about the prevalence mammalian infections. Methods In order understand infection status HEDV humans animals from regions where have isolated, this study used Western blotting detect positive rates IgG antibodies serum samples febrile patients, dogs, chickens forementioned regions. Results results showed 29 human samples, 17.24% (5/29) tested for HEDV, while 68.96% (20/29) were WUXV. 31 dog 87.10% (27/31) 70.97% (22/31) WUXV, 36 chicken 47.22% (17/36) 52.78% (19/36) Discussion These findings suggest there widespread infections mammals (dogs, chickens) isolated. Moreover, rate was higher local compared measured specimens. This first seroepidemiological sandfly-transmitted viruses. practical implications vector-borne viral related zoonotic China, as well providing an important reference studies on relationship between outside China.