Measurement of T1 Mapping in Patients With Cardiac Devices: Off-Resonance Error Extends Beyond Visual Artifact but Can Be Quantified and Corrected

• DOI: 10.3389/fcvm.2021.631366
• Publication Date: 2021-01-29T05:50:06Z
• Authors: Anish N. Bhuva; Thomas A. Treibel; Andreas Seraphim; Paul Scully; Kristopher D. Knott; João B. Augusto; Camilla Torlasco; Katia Menacho; Clement Lau; Kush Patel; James C. Moon; Peter Kellman; Charlotte H. Manisty
• Keywords: Interquartile range; Artifact (error)

Background: Measurement of myocardial T1 is increasingly incorporated into standard cardiovascular magnetic resonance (CMR) protocols, however accuracy may be reduced in patients with metallic implants. feasible segments free from visual artifact, but there still off-resonance induced error. Aim: To quantify error implants, and validate a method for correction conventional MOLLI pulse sequence. Methods: Twenty-four cardiac implantable electronic devices (CIEDs: 46% permanent pacemakers, PPMs; 33% loop recorders, ILRs; 21% cardioverter-defibrillators, ICDs); 31 aortic valve replacement (AVR) (45% metallic) were studied. Paired mid-myocardial short-axis single breath-hold field maps acquired at 1.5 T. values measured by AHA segment, artifact excluded. was applied using published relationship between T1. The the assessed 10 healthy volunteers measuring before after external placement an ICD generator next to chest generate off-resonance. Results: underestimated compared without (967 ± 52 vs. 997 26 ms respectively, p = 0.0001), similar (p 0.57, residual difference 2 27 ms). Artifact visible 4 12, 42 31, 53 27% ILRs, PPMs, ICDs, respectively. In 63 (interquartile range: 7-143) per patient. greatest PPMs ICDs 79, 146, 191 ms, presence AVR did not Conclusion: Even when no CIEDs, AVRs. Off-resonance map acquisition can detect T1, accurately.