Clinical Implications of Phenotypes of Hemodialysis Patients With Central Venous Occlusion or Central Venous Stenosis Defined by Cluster Analysis

• DOI: 10.3389/fcvm.2022.901237
• Publication Date: 2022-06-20T05:34:48Z
• Authors: Chunyong Wen; Bin Chen; Run Lin; Haitao Dai; Keyu Tang; Guiyuan Zhang; Jiawen Huang; Changli Liao; Linyuan Zeng; Xianhong Xiang; Jianyong Yang; Yonghui Huang
• Keywords: Brachiocephalic vein

This study aims to investigate the association between clinical factors of patients with central (superior vena cava, brachiocephalic, or subclavian) venous occlusion stenosis (CVO/CVS) and difficulty interventional recanalization as well duration postoperative patency.A total 103 hemodialysis CVO/CVS treated endovascular treatment were enrolled. The two-step cluster analysis was selected differentiate cases into distinct phenotypes automatically. Differences in characteristics, recanalization, primary patency time two clusters statistically compared.The divided by 48 (46.6%) 1 55 (53.4%) 2. Compared 2, have a higher proportion blunt stump, side branches, lesions >2 cm, calcification, organization. Moreover, above four were, turn, most critical predictors distinguishing clusters. remaining six located superior cava (SVC), catheterization (CVC), lesion location, vessel diameter, number CVC, previously failed lesion. Of important factors, exception exceeding 2 there significant differences length procedure groups grouped three factors. And difference rate group stump without also ≥ cm <2 cm. operation longer than that In terms time, significantly compared (P = 0.025).Patients more challenging be recanalized 1. Blunt calcification organization are