Temporal trends in the prevalence and death of ischemic heart disease in women of childbearing age from 1990 to 2019: a multilevel analysis based on the Global Burden of Disease Study 2019

• DOI: 10.3389/fcvm.2024.1366832
• Publication Date: 2024-04-22T04:52:30Z
• Authors: Ben Hu; Yan Wang; Dong Chen; Jun Feng; Yinguang Fan; Linlin Hou
• Keywords: 03 medical and health sciences; 0302 clinical medicine; women of childbearing age; joinpoint regression; death; RC666-701; prevalence; Diseases of the circulatory (Cardiovascular) system; Global Burden of Disease Study; Cardiovascular Medicine; ischemic heart disease

Background Our objective is to describe the current prevalence and death of ischemic heart disease (IHD) in women childbearing age (WCBA) at global, regional, national levels analyze its temporal trends from 1990 2019. Methods WCBA was defined as aged 15–49 years. Estimates 95% Uncertainty Intervals (UI) IHD numbers for seven groups were extracted 2019 Global Burden Disease Study. The age-standardized rate (ASPR ASDR) estimated using direct age-standardization method. Joinpoint regression analysis used calculate average annual percent change (AAPC) represent Results Between 2019, global ASPR experienced a 3.21% increase, culminating 367.21 (95% UI, 295.74–430.16) cases per 100,000 individuals. Conversely, ASDR decreased 11.11 10.10–12.30) In among five sociodemographic index (SDI) regions, highest observed high-middle SDI region, whereas found low-middle region. Regionally, Caribbean reported (563.11 individuals; 493.13–643.03), Oceania (20.20 13.01–31.03). At level, Trinidad Tobago exhibited (730.15 633.96–840.13), Solomon Islands had (77.77 47.80–121.19). Importantly, over past three decades, has seen significant increase [AAPC = 0.11%, Confidence Interval (CI): 0.09–0.13; P < 0.001], while demonstrated decreasing trend (AAPC −0.86%, CI: −1.11 −0.61; 0.001). Air pollution, tobacco use, high systolic blood pressure, elevated body mass index, dietary risks, LDL cholesterol have been identified leading six risk factors IHD-related deaths Conclusions Despite decline last thirty years, continues escalate. We need remain vigilant about increased burden WCBA. It calls aggressive prevention strategies, rigorous control factors, enhancement healthcare coverage mitigate forthcoming