Magnetic Resonance Imaging Assessment of Abdominal Ectopic Fat Deposition in Correlation With Cardiometabolic Risk Factors

• DOI: 10.3389/fendo.2022.820023
• Publication Date: 2022-03-30T14:41:45Z
• Authors: Qin-He Zhang; Lu-Han Xie; Hao-Nan Zhang; Jing-Hong Liu; Ying Zhao; Li-Hua Chen; Ye Ju; An-Liang Chen; Nan Wang; Qing-Wei Song; Li-Zhi Xie; Ai-Lian Liu
• Keywords: Deposition; Abdominal fat

Purpose Ectopic fat accumulation and abdominal distribution may have different cardiometabolic risk profiles. This study aimed to assess the associations between various magnetic resonance imaging (MRI)-acquired depots factors. Methods A total of 320 subjects with median age 59 years, 148 men 172 women, were enrolled in study. Visceral adipose tissue (VAT) area fraction (FF), subcutaneous (SAT) FF at L1–L2 levels, preperitoneal (pPAT) FF, hepatic pancreatic intramuscular assessed by MRI maps. The MRI-acquired blood pressure, glucose, lipid examined using sex-stratified linear regression. Logistic regression stratified sex was used analyze association hypertension, T2DM, dyslipidemia. Results intraclass correlation coefficient (ICC) values >0.9, which suggested good interobserver intraobserver agreement. VAT area, V/S, fat, pPAT rather than SAT significantly associated multiple factors (all p < 0.05). However, patterns these correlations varied specific Also, only women Conclusions VAT, cardiovascular metabolic independent BMI. related gender. These findings further understanding ectopic deposition help better understand obesity heterogeneity.