Test-takers’ perspectives on consumer genetic testing for hereditary cancer risk

• DOI: 10.3389/fgene.2024.1374602
• Publication Date: 2024-07-10T04:31:53Z
• Authors: Madison K. Kilbride; Lisa Jay Kessler; Brigitte Cronier; Jacqueline J. Park; Cara N. Cacioppo; Jordyn Beem; Angela R. Bradbury
• Keywords: Hereditary Cancer

With few exceptions, research on consumer genetic testing for hereditary cancer risk has focused tests with limited predictive value and clinical utility. Our study advances the existing literature by exploring experiences behaviors of individuals who have taken modern susceptibility that, unlike earlier tests, screen medically significant variants. We interviewed 30 had undergone between 2014 2019. explored participants' pre-test sentiments (7 items), receiving results (5 behavioral health-related changes (6 attitudes beliefs (3 items). Data were analyzed thematic content. Most participants reported a personal (n = 6) and/or family history 24) cancer, which influenced their choice to pursue testing. Before testing, most did not consult physician 25) or receive counseling 23). Nevertheless, majority felt that they understood test-related information 20) 20), though considerable number experiencing negative emotions related results. also shared members 27). Overall, towards predominantly positive This offers new insights into how use perceive risk, focusing perceptions risks, benefits, limitations these services. Understanding test-takers' perspectives can potentially inform improvements aimed at ensuring meet users' needs deliver clinically valuable assessments.