Revealing study and breeding implications for production traits and tail characteristics in Simmental cattle by GWAS

• DOI: 10.3389/fgene.2025.1491816
• Publication Date: 2025-01-31T06:41:50Z
• Authors: Jie Wang; Na Shen; Kaisen Zhao; Jiayu Liao; Genglong Jiang; Jianghai Xiao; Xianbo Jia; Wenqiang Sun; Songjia Lai
• Keywords: Genome-wide Association Study

Simmental cattle are renowned for their dual purpose as meat and dairy breeds. The study recorded phenotype data from 183 performed a Genome-Wide Association Study (GWAS) analysis to elucidate the genetic mechanisms underlying milk production, body size traits, tail characteristics. Statistical of showed that season, parity, age at first calving (AFC) factors had significant effect on production (P < 0.05). results GWAS linear traits revealed candidate genes SH3RF2, DCHS2, ADAMTS1, CAMK4, PPARGC1A, PRL, PRP6, CORIN have been found affect circumference (BC) cannon (CC). Through including Circumference over root (COTR) Tail Length (TL) in cattle, associated with length, such KIF26B, ITPR2, SLC8A1, SLIT3 were identified. Interestingly, IL1RAP, AQP9, PKD2 also metabolic inflammation tails. These markers offer valuable insights into facilitating development molecular breeding strategies enhance value provide references programs.