Emerging role of gut microbiota in autoimmune diseases

• DOI: 10.3389/fimmu.2024.1365554
• Publication Date: 2024-05-03T04:27:57Z
• Authors: Xinyi Wang; Wei Yuan; Chunjuan Yang; Zhangxue Wang; Jin Zhang; Donghua Xu; Xicai Sun; Wenchang Sun
• Keywords: Gut bacteria

Accumulating studies have indicated that the gut microbiota plays a pivotal role in onset of autoimmune diseases by engaging complex interactions with host. This review aims to provide comprehensive overview existing literatures concerning relationship between and diseases, shedding light on interplay microbiota, host immune system. Furthermore, we aim summarize impacts potential mechanisms underlie primarily focusing systemic lupus erythematosus, rheumatoid arthritis, Sjögren’s syndrome, type 1 diabetes mellitus, ulcerative colitis psoriasis. The present will emphasize clinical significance applications interventions based as innovative adjunctive therapies for diseases.