Construction of an aerolysin-based multi-epitope vaccine against Aeromonas hydrophila: an in silico machine learning and artificial intelligence-supported approach

• DOI: 10.3389/fimmu.2024.1369890
• Publication Date: 2024-03-01T04:37:34Z
• Authors: Abdullah S. Alawam; Maher S. Alwethay...
• Keywords: Aerolysin; Docking (animal)

, a gram-negative coccobacillus bacterium, can cause various infections in humans, including septic arthritis, diarrhea (traveler's diarrhea), gastroenteritis, skin and wound infections, meningitis, fulminating septicemia, enterocolitis, peritonitis, endocarditis. It frequently occurs aquatic environments readily contacts leading to high infection rates. This bacterium has exhibited resistance numerous commercial antibiotics, no vaccine yet been developed. Aiming combat the alarmingly rate, this study utilizes