Abdominal venous thromboses: detection of the JAK2 p.V617F mutation by next-generation ultradeep sequencing—A prevalence study of patients in Mecklenburg-West Pomerania (2017–2021)

• DOI: 10.3389/fmed.2023.1344769
• Publication Date: 2024-01-11T04:32:45Z
• Authors: Larissa Henze; Luise Grunwald; Sabine Felser; Maria Witte; Christina Grosse-...; Catrin Roolf; Hugo Murua Escobar; Christian Junghanss
• Keywords: JAK2 V617F; Janus kinase 2

Abdominal venous thromboses are rare thrombotic events with heterogeneous etiologies. They related to myeloproliferative neoplasms (MPNs) in some patients and can occur as first signs of the disease. MPNs characterized by mutations genes Janus kinase 2 (JAK2), leukemia virus oncogene (MPL), calreticulin (CALR).