Denosumab combined with precision radiotherapy for recurrent giant cell tumor of the thoracic spine: a case report and literature review

• DOI: 10.3389/fneur.2023.1308600
• Publication Date: 2024-01-04T05:00:32Z
• Authors: Zukang Miao; Ming Xu; Kai Zheng; Hai Gong; Ning Yan; Qian Chen; Xiuchun Yu
• Keywords: Denosumab; Thoracic spine; Giant Cell Tumors; Curettage

Giant cell tumors of the spine have a high recurrence rate owing to their special anatomical site; hence, further treatment after is very challenging. Achieving effective tumor control and improving long-term quality life patients are main purposes consider for recurrent giant spine. A patient showing thoracic curettage received denosumab combined with precision radiotherapy, by which gained good control, could regain normal functioning. review relevant literature suggested that radiotherapy an new approach