Monipar: movement data collection tool to monitor motor symptoms in Parkinson’s disease using smartwatches and smartphones

• DOI: 10.3389/fneur.2023.1326640
• Publication Date: 2023-12-07T14:16:36Z
• Authors: Luis Sigcha; Carlos Polvorinos...; Nélson Costa; Susana Costa; Pedro Arezes; Miguel Gago; Chaiwoo Lee; Juan Manuel López; Guillermo de Arcas; Ignacio Pavón
• Keywords: resting tremor; mHealth; Neurology; bradykinesia; 0202 electrical engineering, electronic engineering, information engineering; Neurology. Diseases of the nervous system; 02 engineering and technology; RC346-429; mobile health; inertial sensors

IntroductionParkinson’s disease (PD) is a neurodegenerative disorder commonly characterized by motor impairments. The development of mobile health (m-health) technologies, such as wearable and smart devices, presents an opportunity for the implementation of clinical tools that can support tasks such as early diagnosis and objective quantification of symptoms.ObjectiveThis study evaluates a framework to monitor motor symptoms of PD patients based on the performance of standardized exercises such as those performed during clinic evaluation. To implement this framework, an m-health tool named Monipar was developed that uses off-the-shelf smart devices.MethodsAn experimental protocol was conducted with the participation of 21 early-stage PD patients and 7 healthy controls who used Monipar installed in off-the-shelf smartwatches and smartphones. Movement data collected using the built-in acceleration sensors were used to extract relevant digital indicators (features). These indicators were then compared with clinical evaluations performed using the MDS-UPDRS scale.ResultsThe results showed moderate to strong (significant) correlations between the clinical evaluations (MDS-UPDRS scale) and features extracted from the movement data used to assess resting tremor (i.e., the standard deviation of the time series: r = 0.772, p < 0.001) and data from the pronation and supination movements (i.e., power in the band of 1–4 Hz: r = −0.662, p < 0.001).ConclusionThese results suggest that the proposed framework could be used as a complementary tool for the evaluation of motor symptoms in early-stage PD patients, providing a feasible and cost-effective solution for remote and ambulatory monitoring of specific motor symptoms such as resting tremor or bradykinesia.