Involvement of the posterior limb of the internal capsule independently predicts the prognosis of patients with basal ganglia and thalamic hemorrhage

• DOI: 10.3389/fneur.2024.1475444
• Publication Date: 2025-01-07T05:35:00Z
• Authors: Sohan Gupta; Mengxuan Xiao; Na Liu; Yunxiao Zhao; Xiaolin Zhao; Yunqiang Huang; Yongming Wu; Zhenzhou Lin; Zhong Ji; Haihao Xu; Minzhen Zhu; Suyue Pan; Kaibin Huang
• Keywords: Basal (medicine)

Intracerebral hemorrhage (ICH) is the most lethal and devastating subtype of stroke. Basal ganglia thalamic are common types ICH, accounting for 50-70% all ICH cases, leading to disability death, it involves posterior limb internal capsule varying degrees. In this study, we investigated impact degrees involvement on prognosis patients with basal assessed whether improves predictive accuracy max-ICH score, an existing scale functional outcome. This a multicenter, retrospective, observational study. We graded according degree compression injury (called iICH, ranging from 0 4). An unfavorable outcome was defined as 90-day modified Rankin Scale (mRS) > 2. Multivariate logistic regression analysis used identify independent risk factors associated prognosis. The discrimination verified using receiver operating characteristic curve (ROC) analysis, while calibration by Hosmer-Lemeshow test. Of 305 included, 188 Nanfang Hospital were assigned development cohort, 117 Heyuan People's Huadu District validation cohort. iICH identified factor outcome, area under ROC (AUC) 0.774. When combined AUC significantly elevated 0.816 0.866. Comparable results found in Increased worse ICH.