Total sleep deprivation selectively impairs motor preparation sub-stages in visual search task: Evidence from lateralized readiness potentials

• DOI: 10.3389/fnins.2023.989512
• Publication Date: 2023-02-28T04:43:26Z
• Authors: Tao Song; Fangchong Du; Lin Xu; Ziyi Peng; Letong Wang; Cimin Dai; Mengmeng Xu; Ying Zhang; Yongcong Shao; Xiechuan Weng; Shijun Li
• Keywords: Visual Search; Sleep

Many studies have provided evidence of a damage effect triggered by total sleep deprivation (TSD). However, it remains unclear whether the motor preparation processing is affected TSD.In current study, 23 volunteers performed stimulus-response compatibility visual search task before and after TSD while undergoing spontaneous electroencephalography (EEG).Repeated-measures analysis variance revealed that: Compared with that at baseline, task's accuracy decreased TSD, response time increased significantly. The peak amplitude stimulus-locked lateralized readiness potential (LRP) induced compatible stimulus was significantly more negative than an incompatible whereas this difference not significant TSD. when taking status into consideration, there were no main or interaction effects on response-locked LRPs.Our findings suggest damages behavior, selectively impairs earlier sub-stages (sensory integration). These will provide new perspective for understanding loss.