State- and Condition-Dependent Modulation of the Hindlimb Locomotor Pattern in Intact and Spinal Cats Across Speeds

• DOI: 10.3389/fnsys.2022.814028
• Publication Date: 2022-02-09T05:48:10Z
• Authors: Jonathan Harnie; Johannie Audet; Stephen Mari; Charly G. Lecomte; Angèle N. Merlet; Gabriel Genois; Ilya A. Rybak; Boris I. Prilutsky; Alain Frigon
• Keywords: Hindlimb; Quadrupedalism; Treadmill

Locomotion after complete spinal cord injury (spinal transection) in animal models is usually evaluated a hindlimb-only condition with the forelimbs suspended or placed on stationary platform and compared quadrupedal locomotion intact state. However, because of nature movement these animals, play an important role modulating hindlimb pattern. This raises question: whether changes pattern transection are due to state system (intact versus spinal) hindlimb-only. We collected kinematic electromyographic data during at seven treadmill speeds before nine adult cats attribute some state, such as convergence stance swing durations high speed, improper coordination ankle hip joints, switch timing knee flexor bursts, modulation burst incidence bi-phasic bursts muscles. Alternatively, relate locomotion, paw placement relative contact, magnitude yield, muscles their timing. Overall, we show greater similarity spatiotemporal EMG variables between two conditions, suggesting that more appropriate pre-spinal control rather than locomotion.