Is preoperative ultrasound tumor size a prognostic factor in endometrial carcinoma patients?

• DOI: 10.3389/fonc.2022.993629
• Publication Date: 2022-09-23T11:22:24Z
• Authors: Marco Ambrosio; Antonio Raffone; Andrea Alletto; Chiara Cini; Francesco Filipponi; Daniele Neola; Matilde Fabbri; Alessandro Arena; Diego Raimondo; Paolo Salucci; Manuela Guerrini; Antonio Travaglino; Roberto Paradisi; Antonio Mollo; Renato Seracchioli; Paolo Casadio
• Keywords: relapse; tumor; recurrence; risk assessment; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Oncology; death; cancer; prognosis; RC254-282; cancer; death; prognosis; recurrence; relapse; risk assessment; tumor

We aimed to assess the prognostic value of preoperative ultrasound tumor size in EC through a single center, observational, retrospective, cohort study. Medical records and electronic clinical databases were searched for all consecutive patients with EC, scans available ad hoc estimate size, follow-up at least 2-year, our Institution from January 2010 June 2018. Patients divided into two groups based on different dimensional cut-offs maximum diameter: 2, 3 4 cm. Differences overall survival (OS), disease specific (DSS) progression-free (PFS) assessed among by using Kaplan-Meier estimator log-rank test. 108 included OS, DSS PFS did not significantly differ between diameter cut-offs. No significant differences found sub-stratified age, BMI, FIGO stage, grade, lymphovascular space invasion status, myometrial invasion, lymph nodal involvement, histotype, adjuvant treatment. Preoperative does appear as factor women.