Memory deficit following resection of an intraventricular myxoid glioneuronal tumor impinging on the bilateral fornix: A case report

• DOI: 10.3389/fonc.2023.1263556
• Publication Date: 2023-09-28T05:57:23Z
• Authors: Alena Stasenko; Erik Kaestner; Jonathan Rodriguez; Jiwandeep S. Kohli; Nikdokht Farid; Vanessa Goodwill; Marc S. Schwartz; Jessica D. Schulte; Carrie R. McDonald
• Keywords: Fornix; Septum pellucidum

Background Recently recognized as a distinct entity, myxoid glioneuronal tumor (MGNT) is rare, low-grade central nervous system tumor. MGNTs are commonly located at the septum pellucidum or in third ventricle, increasing likelihood of treatment-related damage to adjacent structures critical for memory, such fornix. Though there have been handful case reports neurosurgical and oncological outcomes MGNTs, memory following resection fornix not previously reported. Methods We present high functioning female whom an MRI revealed incidental finding intraventricular bilaterally. The patient underwent followed by surveillance without additional oncologic intervention. Due reported cognitive problems, was referred serial neuropsychological evaluations. Results Post-operative cytotoxic edema selective, progressive atrophy bilateral anterior fornices. Post-surgically, developed isolated verbal impairment, which persisted one-year post with minimal improvement. impairment impacted patient’s everyday functioning, including ability work cognitively demanding job. Conclusion This unique demonstrates role underscores importance careful risk/benefit analysis when considering intervention other intracranial lesions this structure during planning.