Handgrip strength assessment at baseline in addition to bone parameters could potentially predict the risk of curve progression in adolescent idiopathic scoliosis

• DOI: 10.3389/fped.2023.1258454
• Publication Date: 2023-11-03T09:50:21Z
• Authors: Rufina Wing Lum Lau; Ka Yee Cheuk; Vivian Wing Yin Hung; Fiona Wai Ping Yu; Elisa Man Shan Tam; Lyn Lee Ning Wong; Jiajun Zhang; Wayne Yuk Wai Lee; Jack Chun Yiu Cheng; Tsz Ping Lam; Adam Yiu Chung Lau
• Keywords: Cobb angle

Adolescent idiopathic scoliosis (AIS) is characterized by deranged bone and muscle qualities, which are important prognostic factors for curve progression. This retrospective case-control study aims to investigate whether the baseline parameters, in addition could predict progression AIS.The included a cohort of 126 female patients diagnosed with AIS who were between ages 12 14 years old at their initial clinical visit. These longitudinally followed up every 6 months (average 4.08 years) until they reached skeletal maturity. The records these thoroughly reviewed as part study. participants categorized into two sub-groups: progressive group (increase Cobb angle ≥6°) stable <6°). Clinical radiological assessments conducted on each group.Cobb increase ≥6° was observed 44 (34.9%) prior A associated decreased maturity weight, lower trunk lean mass (5.7%, p = 0.027) arm (8.9%, < 0.050), weaker dominant handgrip strength (8.8%, 0.027), cortical compartment [lower volumetric mineral density (vBMD) 6.5%, 0.002], mechanical properties [stiffness estimated failure load lowered 13.2% (p 0.005) 12.5% 0.004)]. best cut-off threshold maximum 19.75 kg distinguishing from (75% sensitivity 52.4% specificity, 0.011).Patients had poorer parameters than AIS. implementation potentially be used an additional predictor, identifying individuals higher risk experiencing