MOSkin dosimetry for an ultra-high dose-rate, very high-energy electron irradiation environment at PEER

• DOI: 10.3389/fphy.2024.1401834
• Publication Date: 2024-07-30T04:51:25Z
• Authors: James Cayley; Yaw-Ren E. Tan; Marco Petasecca; Dean Cutajar; Thomas Breslin; Anatoly Rosenfeld; Michael Lerch
• Keywords: Dose rate; High energy

FLASH radiotherapy, which refers to the delivery of radiation at ultra-high dose-rates (UHDRs), has been demonstrated with various forms and is subject intense research development recently, including use very high-energy electrons (VHEEs) treat deep-seated tumors. Delivering radiotherapy in a clinical setting expected place high demands on real-time quality assurance dosimetry systems. Furthermore, electron currently requires transformation existing non-medical accelerators into environments. Accurate crucial for any such transformation. In this article, we assess response MOS kin , developed by Center Medical Radiation Physics, designed on-patient, skin dose measurements during whether it exhibits dose-rate independence when exposed 100 MeV beams Pulsed Energetic Electrons Research (PEER) end-station. PEER utilizes beam from linear accelerator not used as injector ANSTO Australian Synchrotron. With estimated pulse ranging <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="m1"><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mn>7.84</mml:mn><mml:mo>±</mml:mo><mml:mn>0.21</mml:mn></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow><mml:mo>×</mml:mo><mml:mn>1</mml:mn><mml:msup><mml:mrow><mml:mn>0</mml:mn></mml:mrow><mml:mrow><mml:mn>5</mml:mn></mml:mrow></mml:msup></mml:math> Gy/s id="m2"><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mn>1.28</mml:mn><mml:mo>±</mml:mo><mml:mn>0.03</mml:mn></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow><mml:mo>×</mml:mo><mml:mn>1</mml:mn><mml:msup><mml:mrow><mml:mn>0</mml:mn></mml:mrow><mml:mrow><mml:mn>7</mml:mn></mml:mrow></mml:msup></mml:math> an peak bunch id="m3"><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mn>2.55</mml:mn><mml:mo>±</mml:mo><mml:mn>0.06</mml:mn></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow><mml:mo>×</mml:mo><mml:mn>1</mml:mn><mml:msup><mml:mrow><mml:mn>0</mml:mn></mml:mrow><mml:mrow><mml:mn>8</mml:mn></mml:mrow></mml:msup></mml:math> Gy/s, were verified against scintillating screen confirm that responds proportionally charge delivered and, therefore, irradiation environment.