The Effects of Acute Aerobic Exercise on Blood Pressure, Arterial Function, and Heart Rate Variability in Men Living With HIV

• DOI: 10.3389/fphys.2021.685306
• Publication Date: 2021-07-15T15:06:36Z
• Authors: Juliana Pereira B...; Tainah de Paula; Mauro Felippe Fel...; Marcus Vinicius d...; Walace Monteiro; Felipe Amorim da ...; Paulo Farinatti; Juliana Pereira B...
• Keywords: Aerobic Exercise

Purpose This study aims to investigate the effects of acute cycling on blood pressure (BP), arterial function, and heart rate variability (HRV) in men living with HIV (MLHIV) using combined antiretroviral therapy (cART). Methods Twelve MLHIV (48.7 ± 9.2 years; 25.2 2.8 kg m –2 ) 13 healthy controls (41.2 9.9 26.3 2.9 performed a bout (ES) (intensity: 50% oxygen uptake reserve; duration: time achieve 150 kcal—MLHIV: 24.1 5.5 vs. controls: 23.1 3.0 min; p = 0.45), 20-min non-exercise session (NES). Results At rest ( < 0.05), presented higher brachial systolic/diastolic BP (SBP/DBP: 123.2 14.2/76.8 6.3 114.3 5.1/71.6 2.6 mmHg) central (cSBP/cDBP: 108.3 9.3/76.5 6.5 101.6 4.9/71.3 4.4 but lower absolute maximal (2.1 0.5 2.5 0.3 L min –1 HRV indices reflecting overall/vagal modulation (SDNN: 24.8 7.1 42.9 21.3 ms; rMSSD: 20.5 8.5 38.1 22.8 pNN50: 3.6 4.2 13.6 11.3%). DBP postexercise lowered (∼4 mmHg, 0.001; ES: 0.6). Moreover, had greater reductions 0.05) augmentation index (−13.6 13.7 −3.1 7.2% ; 2.4), up 5 (rMSSD: −111.8 32.1 −75.9 22.2 ms 3.8; −76.3 28.3 −19.0 13.7% 4.4). Within-group (ES NES; occurred for SBP (∼10 2 h), (∼6 20, 30, 70 min), cSBP (∼9 30 cDBP (∼7 (∼10%, pNN50 (∼20%; while only min) decreased. Similar increases (up (∼22 bpm) decreases SDNN (∼18 ms) rMSSD (∼20 both groups. Conclusion under cART exhibited attenuated hypotension controls, which seemed relate impairments vascular function.